closed-loop supply chain network design is a critical issue due to its impact on both economic and environmental performances of the supply chain. in this paper, we address the problem of designing a multi-echelon, multi-product and capacitated closed-loop supply chain network. first, a mixed-integer linear programming formulation is developed to maximize the total profit. the main contribution...

This paper develops a model for the closed-loop supply chain network design with disruption risk. By considering supply disruption, two factors including extra inventory and lateral transshipment are used as resilience strategies. The main purpose is to reduce the supply chain costs due to the location decisions, quantity of products between different levels and lost sale. Disruption in a suppl...

1 Cancer and Radiation Epidemiology Unit, Gertner Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel. 2 Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. 3 Radiation Group, International Agency for Research on Cancer, Lyon, France. 4 Department of Otolaryngology–Head and Neck Surgery, Chaim Sheba Medical Center, Tel Hashomer, Israel. 5 Biostatistics Unit, Gertner Insti...

Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Pediatric Hematology-Oncology, The Chaim Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Israel; Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel; Functional Genomics Unit, The Chaim Sheba Medical Center and Sackler School of Medicin...

this paper proposes a new mixed integer programming model for multi-item capacitated lot-sizing problem with setup times, safety stock and demand shortages in closed-loop supply chains. the returned products from customers can either be disposed or be remanufactured to be sold as new ones again. due to the complexity of problem, three meta-heuristics algorithms named simulated annealing (sa) al...

green supply chain management is an environmental approach in supply chain management that aims to decrease ecological risks in products’ life cycle. closed-loop supply chain by collecting and recycling the harmful production in nature attempts to achieve this goal. in this paper, due to different strategies in collecting products, several pricing models in two-echelon closed supply chain are p...

Tibial Amputees 1Portnoy S., 2Shabshin N., 2Itzchak Y., 3Yizhar Z., 4Dotan-Marom Y., 4Oppenheim U., 4Siev-Ner I. and Gefen A. 1Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel 2Diagnostic Imaging, Chaim Sheba Medical Center, Israel Physical Therapy, Tel Aviv University, Israel Orthopaedic Rehabilitation Department, Chaim Sheba Medical Center, Israel Web: www.eng.tau.ac.il/~msbm , e...